Breast cancer cell invasion is complex due to diverse microenvironmental factors, making it challenging to study using conventional in vitro models such as Matrigel. This solution introduces a decellularized extracellular matrix (ECM) from pig hearts as a more physiologically relevant model for breast cancer research. By converting this ECM into a hydrogel and assessing its impact on MCF-7 cell migration and invasion, the model provides a more accurate tool for evaluating cancer progression and drug efficacy, overcoming limitations of traditional methods
Nanyang Technological University
Targeted antimicrobial treatment for resistant infections