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Decellularized ECM model for breast cancer studies

Breast cancer cell invasion is complex due to diverse microenvironmental factors, making it challenging to study using conventional in vitro models such as Matrigel. This solution introduces a decellularized extracellular matrix (ECM) from pig hearts as a more physiologically relevant model for breast cancer research. By converting this ECM into a hydrogel and assessing its impact on MCF-7 cell migration and invasion, the model provides a more accurate tool for evaluating cancer progression and drug efficacy, overcoming limitations of traditional methods

Team

  • Diana Carolina Peña Córdova

    Diana Carolina Peña Córdova

    Universidad de Ingeniería y Tecnología – UTEC

    Bioengineer senior student, interested in tissue engineering and biomaterials research fields. With international research experience (work in laboratories in Canada, France, and Argentina) in biomaterial synthesis, and biological, chemical, and mechanical characterization of materials for biomedical applications.more

  • Alejandro Javier Iza Zurita

    Alejandro Javier Iza Zurita

    Universidad de Ingeniería y Tecnología – UTEC

    Bachelor in Bioengineering from the University of Engineering and Technology (UTEC). Passionate about innovation and agile methodologies for project development. My interest focuses on the application of biotechnology to solve environmental, agricultural and industrial problems. My goal is to become a leading professional and grow both intellectually and personally, using empathy as my banner.more

  • Luz Narciza Pérez-Tulich

    Universidad de Ingeniería y Tecnología – UTEC

    Biologist graduated from the Universidad Nacional de San Agustín (Arequipa – Peru). Master of Science with a mention in immunology from the Universidad Peruana Cayetano Heredia (Lima- Peru). I have experience in Microbiology, Biomaterials, Cell Cultures and 3D Bioprinting. Currently, I am responsible for the Tissue Engineering and Synthetic Biology Laboratory at the Universidad de Ingenieria y Tecnologia – UTEC (Lima- Peru). more

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