Gastric Infection Therapy

Gastric Infection Therapy

Project Overview

Year

About

This research explores a novel immunotherapy for Helicobacter pylori, a bacterium linked to ulcers and gastric cancer. Instead of antibiotics, it uses antibodies from immunised hens to block a protein essential for the bacterium’s survival. In lab tests, these antibodies cut the activity of urease, an enzyme H. pylori uses to neutralize stomach acid, by more than 84%, and inhibit bacterial growth. The approach shows promise as a safer, resistance-free alternative to antibiotics, potentially offering new hope for millions affected by this widespread infection

Team

Shaho Menbari

Shaho Menbari

Sara Kamal Shahsavar

Sara Kamal Shahsavar

Mashhad University of Medical Sciences

Sara is a researcher with a Master of Science in Medical Microbiology from Mashhad University of Medical Sciences, Iran. Her thesis explored the inhibitory potential of IgY antibodies in the treatment and prophylaxis of Helicobacter pylori infection. Sara's academic journey began when she earned her Bachelor of Science in Cellular and Molecular Biology. Her research interests span the development of novel biomedical applications of natural compounds, with a focus on the therapeutic potentials of antibodies. Her research interests include Gene expression, Recombinant Protein Expression and Purification, and Plasmid Cloning."

Nima Hajinajaf

Nima Hajinajaf

Zahra Esmaeili

Zahra Esmaeili

Hamid Ariannejad

Hamid Ariannejad

Gallery

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